Diagnosis of human papillomavirus (HPV) involves not only detecting the virus, but determining which of the more than 100 related viruses that make up HPV is present.Though most are relatively harmless, it's especially important to find out if the infection involves one of the more than 14 high-risk strains that are strongly linked to cancer Human papillomaviruses (HPVs) comprise more than 100 genotypes. The mucosal types can be divided into high-risk and low-risk (LR) types depending on the associated disease risk. HPV infection is mainly diagnosed by molecular methods, since reliable serological tools are not available and culture of the virus is not possible
Human papillomavirus (HPV) is the most common sexually transmitted infection in the United States, affecting men and women. 1 It is estimated that more than 24 million men and women in the United States are currently infected with HPV. 2, 3 More than 4 million new HPV infections are reported in the United States annually, and about 1%-10% of the sexually active U.S. population is infected at any given time. 4, 5 There are 2 categories of HPV: those infections that are passed through skin. Fig. 1. Detection of HPV DNA in Pap smears. (A) A Pap smear that was within normal limits; HPV DNA was detected using the hybrid capture system (not shown).However, HPV DNA was not detected by in situ hybridization (A, pink is negative and blue is positive).(B) Specimen is from a woman with a Pap smear diagnosis of ASCUS.HPV DNA was detected by the hybrid capture system and in situ. Human papillomavirus (HPV). Verruca vulgaris on the lateral border of the tongue exhibits the multiple, sharp-tipped, white, verrucous appearance, which is classic for this lesion in the oral cavity. Not all verrucae are so clinically diagnostic. Courtesy of Rose Yin Geist, DDS Human papillomavirus (HPV) is a group of viruses that are extremely common worldwide. There are more than 100 types of HPV, of which at least 14 are cancer-causing (also known as high risk type). HPV is mainly transmitted through sexual contact and most people are infected with HPV shortly after the onset of sexual activity Human papillomavirus testing by hybrid capture appears to be useful in triaging women with a cytologic diagnosis of atypical squamous cells of undetermined significance Am J Obstet Gynecol. , 172 ( 1995 ) , pp. 946 - 95
Molecular diagnosis of human papillomavirus (HPV) infections Anco Molijn∗, Berhard Kleter, Wim Quint, Leen-Jan van Doorn DDL, Fonteynenburghlaan 5, 2275 CX Voorburg, The Netherlands Received 26 July 2004; accepted 6 December 2004 Abstract Human papillomaviruses (HPVs) comprise more than 100 genotypes Approximately 100 types of human papillomavirus infection (HPV) have been identified, at least 40 of which can infect the genital area . Most HPV infections are self-limited and are asymptomatic or unrecognized. Most sexually active persons become infected with HPV at least once in their lifetime (533,759) Human papillomavirus (HPV) DNA tests tend to show high sensitivity, but poor specificity in detecting high-grade cervical lesions. This study aimed to explore the clinical performance of QuantiVirus(®) HPV E6/E7 mRNA in identifying ≥Grade 2 cervical intraepithelial neoplasia Significant declines in the frequency of vaginal and oral sexual behaviors were reported at follow-up, regardless of tumor HPV status. From baseline to 6 months, significant increases in abstinence from vaginal sex (from 10% to 34%; P < .01) and oral sex (from 25% to 80%; P < .01) were reported
Human papillomavirus infection (HPV infection) is an infection caused by human papillomavirus (HPV), a DNA virus from the Papillomaviridae family. Many HPV infections cause no symptoms and 90% resolve spontaneously within two years. However, in some cases, an HPV infection persists and results in either warts or precancerous lesions Meisels A. Cytologic diagnosis of human papillomavirus. Influence of age and pregnancy stage. Acta Cytol. 1992 Jul-Aug. 36(4):480-2. . Evander M, Edlund K, Gustafsson A, Jonsson M, Karlsson R. Papillomaviruses are double-stranded DNA viruses that constitute the Papillomavirus genus of the Papillomaviridae family. These viruses are highly species specific; human papillomaviruses (HPV) infect only humans. There are more than 200 types of HPV, which can be subdivided into cutaneous or mucosal categories based upon their tissue tropism Cervical cancer arises via the following steps: infection of the cervical epithelium with 1 or more of the ∼ 15 carcinogenic human papillomavirus (HPV) genotypes, persistence of the infection, neoplastic progression to cervical precancer, and invasive cancer [ 1 ]
What is human papillomavirus (HPV)? Human papillomavirus (HPV) is a common sexually transmitted virus. It is the most common sexually transmitted infection (STI) in the United States. There are more than 100 types of HPV. Some types don't cause any symptoms. Other types cause genital warts SUMMARY High-risk human papillomaviruses (HPVs) cause essentially all cervical cancers, most anal and oropharyngeal cancers, and some vaginal, vulvar, and penile cancers. Improved understanding of the pathogenesis of infection and the availability of newer tests are changing the approach to screening and diagnosis. Molecular tests to detect DNA from the most common high-risk HPVs are FDA. Abstract. Human papillomaviruses (HPVs) comprise more than 100 genotypes. The mucosal types can be divided into high-risk and low-risk (LR) types depending on the associated disease risk. HPV infection is mainly diagnosed by molecular methods, since reliable serological tools are not available and culture of the virus is not possible DIAGNOSIS OF HUMAN PAPILLOMAVIRUS GYNECOLOGIC INFECTIONS 279 ture System (HCS, Digene Diagnostic, Silver Springs, MD) it was never widely used in the clinical laboratory setting. ISH is a third nonamplification technique applied to histologic sections or cell smears. This method involves gentle enzymatic or detergent treatment to permeabilize.
Journal of Clinical Virology 32S (2005) S43-S51 Review Molecular diagnosis of human papillomavirus (HPV) infections Anco Molijn∗ , Berhard Kleter, Wim Quint, Leen-Jan van Doorn DDL, Fonteynenburghlaan 5, 2275 CX Voorburg, The Netherlands Received 26 July 2004; accepted 6 December 2004 Abstract Human papillomaviruses (HPVs) comprise more than 100 genotypes Molecular Diagnosis of Human Papillomavirus Infections, Human Papillomavirus and Related Diseases From Bench to Bedside A Diagnostic and Preventive Perspective, Davy Vanden Broeck, IntechOpen, DOI: 10.5772/55706. Available from: Over 21,000 IntechOpen readers like this topic. Help us write another book on this subject and reach those readers. Human papillomaviruses (HPVs) comprise more than 100 genotypes. The mucosal types can be divided into high-risk and low-risk (LR) types depending on the associated disease risk. HPV infection is mainly diagnosed by molecular methods, since reliable serological tools are not available and culture of the virus is not possible. Accurate molecular diagnostic techniques that can be used to inform. The diagnostic utility of human papillomavirus-testing in combination with immunohistochemistry in advanced gynaecologic pelvic tumours: a new diagnostic approach. Int J Oncol 2004;24(4):829-836. 50. Bauer HM, Ting Y, Greer CE, Chambers JC, Tashiro CJ, Chimera J, et al. Genital human papillomavirus infection in female university students as.
Discussing a diagnosis of human papillomavirus oropharyngeal cancer with patients: An exploratory qualitative study of health professionals. Rachael H. Dodd MSc. Department of Epidemiology and Public Health, Cancer Research United Kingdom Health Behaviour Research Centre, London, United Kingdom 1. Introduction. Human papillomavirus (HPV) infections are one of the most common sexually transmitted infections worldwide , representing a significant health problem due to their high prevalence and transmissibility.HPVs are a very large family of double-stranded DNA viruses (dsDNA), very resistant that can survive in the environment without a host and is able to infect humans The diagnostic efficiency of AUC by applying HPV16/18 viral load was 0.682 for the diagnosis of CIN II+. The optimal HPV16/18 viral load for predicting CIN II+ was 6.80 RLU/CO (relative light units/cut-off), with corresponding sensitivity of 48.6%, specificity of 79.7%, and Youden index of 0.283
Meisels A. Cytologic diagnosis of human papillomavirus. Influence of age and pregnancy stage. Acta Cytol. 1992 Jul-Aug. 36(4):480-2. . Evander M, Edlund K, Gustafsson A, Jonsson M, Karlsson R, Rylander E, et al. Human papillomavirus infection is transient in young women: a population-based cohort study. J Infect Dis. 1995 Apr. 171(4):1026-3
Most human papillomavirus (HPV) infections of the genitals cause no symptoms and disappear on their own within two years. There are many different strains of the virus, though just a few can cause genital warts or lead to more serious complications, such as cancer.. Though there's no cure for HPV infection, NYU Langone doctors can create treatment plans for the conditions it can cause, such. The diagnostic efficiency of AUC by applying HPV16/18 viral load was 0.682 for the diagnosis of CIN II+. The optimal HPV16/18 viral load for predicting CIN II+ was 6.80 RLU/CO (relative light units/ cut-off), with corresponding sensitivity of 48.6%, specificity of 79.7%, and Youden index of 0.283 To describe initial presentations and idiosyncrasies in establishing the diagnosis for human papillomavirus‐related (HPV +) compared to HPV‐unrelated (HPV −) oropharyngeal carcinoma (OPC). Study Design. A single institution retrospective series derived from an institutional prospectively compiled database supplemented by chart review. Method The human papillomavirus (HPV) is responsible for a common sexually transmitted infection that shares the same name. Most sexually active people are exposed to it at some point
Human papillomaviruses cause the most common sexually trans- mitted infection in the world and are responsible for nearly all cases of cervical cancer. Genital human papillomavirus infection can. Human papillomavirus DNA is detected in 80% to 100% of tumors showing these differentiation patterns. 2 Human papillomavirus DNA is only very rarely detected in the nonmucinous types of ADC, such as clear cell, serous, and mesonephric adenocarcinoma. 2,8 In addition, gastric type, which includes minimal-deviation adenocarcinoma, was shown to be. Genital warts are a very common STI. Caused by human papillomavirus (HPV) infection, most commonly HPV types 6 and 11. Peak incidence of genital HPV infection occurs in 16- to 25-year-olds. Diagnosis is made based on clinical presentation. Generally has a benign course and is not often associated..
Among the risk factors that influence the development and genesis of this cancer, in addition to human papillomavirus (fundamentally, Types 16, 18 and 31), are poor hygiene, chronic anal irritation, smoking, seropositivity for herpes virus, seropositivity for human immunodeficiency virus, sexual promiscuity, passive anal sex, anal fistulas and. Human papillomavirus-associated oropharyngeal cancer: an observational study of diagnosis, prevalence and prognosis in a UK population BMC Cancer. , 13 ( 2013 ) , p. 220 , 10.1186/1471-2407-13-22 . Although we have developed preventive vaccines that can protect from HPV infection, there are still many new cases of HPV-related cancers worldwide. Early diagnosis and therapy are therefore important for the treatment of these diseases What is HPV (human papillomavirus)? HPV is a group of more than 200 related viruses, some of which are spread through vaginal, anal, or oral sex. Sexually transmitted HPV types fall into two groups, low risk and high risk. Low-risk HPVs mostly cause no disease. However, a few low-risk HPV types can cause warts on or around the genitals, anus, mouth, or throat Human papillomavirus (HPV) is the most common sexually transmitted infection among humans, and represents a well-established cause of cervical cancer in females and a significant factor in the development of anogenital, head, and neck cancers .A number of investigations have found that HPV infection may also be transmitted by nonsexual routes , as HPV DNA has been detected in blood and in.
Human papillomavirus is a very common virus that can be transmitted by skin-to-skin contact and infects the skin or mucous membranes. There are more than 100 different identified genotypes of HPV, each assigned a specific number. This article will focus on those genotypes that can be transmitted by sexual contact and are responsible for the. Testing for human papillomavirus (HPV) HPV testing is part of cervical screening. There's no blood test for HPV. During cervical screening, a small sample of cells is taken from the cervix and tested for HPV. Screening is offered to all women and people with a cervix aged 25 to 64. It helps protect them against cervical cancer
MOLECULAR MARKERS FOR THE DIAGNOSIS OF HIGH-RISK HUMAN PAPILLOMAVIRUS INFECTION AND TRIAGE OF HUMAN PAPILLOMAVIRUS-POSITIVE WOMEN Kirvis Torres-Poveda 1,2, Patricia Piña-Sánchez 3, Verónica Vallejo-Ruiz 4, Marcela Lizano 5, Aurelio Cruz-Valdez 6, Paula Juárez-Sánchez 7, Jaime de la Garza-Salazar 7, Joaquín Manzo-Merino 8,9 *. 1 Center for Research in Infectious Diseases, Instituto. Additional information. Description. The global Human Papillomavirus (HPV) molecular diagnostics market was valued at $ 87.3 Million in 2017 and is forecast to grow at a modest 10.40 % CAGR between 2018 and 2025, culminating in 2025 global sales of $ 174.5 Million An HPV test looks for high-risk HPV (human papillomavirus) infections in women. HPV is the most common sexually transmitted disease. Most infections aren't serious. But some high-risk HPV infections can cause cervical and other types of cancer. Learn more Human papillomavirus infection is a major cause of cervical cancer, vulvar cancer, vaginal cancer, penis cancer, anal cancer, and HPV-positive oropharyngeal cancers. Most viral warts are caused by human papillomavirus infection (HPV), of which there are nearly 200 distinct human papillomaviruses (HPVs), and many HPV types are carcinogenic. Cervical cancer is the second most common cancer in the world's woman population with a high incidence in developing countries where diagnostic conditions for the cancer are poor. The main culprit causing the cancer is the human papillomavirus (HPV). HPV is divided into three major groups, i.e., high-risk (HR) group, probable high-risk (pHR) group, and low-risk (LR) group according to their.
Human papillomavirus (HPV) that occurs in the mouth is a sexually transmitted infection (STI). It often has few or no symptoms, which is why getting regularly tested is important. More than 100. Genital human papillomavirus (HPV) infection is a common sexually transmitted infection (STI) caused by human papillomavirus. There are several different strains, some of which can cause cancer The human papillomavirus (HPV) is a collection of viruses that can cause warts on any part of your body. Some strains of HPV are spread through sexual contact with an infected person and can result in genital warts, which is a sexually transmitted disease (STD). Sexually transmitted HPV can also affect the mouth, throat, and anus
Human Papillomavirus Type 16. Human papillomavirus is a small, non-enveloped, double-stranded DNA virus that is approximately 55 nm in diameter. The virus has an icosahedral shell primarily consisting of 360 molecules of the L1 major capsid protein arranged as surface 72 pentamers (light blue) Cervical cancer arises via the following steps: infection of the cervical epithelium with 1 or more of the ∼ 15 carcinogenic human papillomavirus (HPV) genotypes, persistence of the infection, neoplastic progression to cervical precancer, and invasive cancer .Women may have multiple concurrent and sequential infections with different types, and most infections clear within 1-2 years  Gillison, M, D'Souza, G, Westra, W et al. Distinct risk factor profiles for human papillomavirus type 16-positive and human papillomavirus type 16-negative head and neck cancers. J Natl Cancer Inst. 2008; 100 (6): 407 - 420.Google Scholar PubMe In a feasibility study using a prototype, lateral-flow test for human papillomavirus type 16, 18, and/or 45 (HPV16/18/45) E6 oncoproteins, 51 of 75 (68%; 95% confidence interval [95% CI] of 56 to 78%) of HPV16/18/45 DNA-positive specimens from women with a diagnosis of CIN3+ (cervical intraepithelial neoplasia grade 3+ or cervical cancer) tested positive for HPV16/18/45 E6 oncoprotein. None of.
Human papillomavirus (HPV) is the leading cause of cervical cancer. Urine-based HPV testing offers a simple and non-invasive method because of its increasing acceptance. A total of 164 pairs of cervical swab and urine samples from Thai women who underwent cervical cancer screening were used for HPV testing with HPV GenoArray Diagnostic Kits Gardasil (sold by Merck & Co.) is a vaccine that protects against human papillomavirus types 6, 11, 16 and 18. Types 6 and 11 cause genital warts, while 16 and 18 cause cervical cancer.The vaccine is preventive, not therapeutic, and must be given before exposure to the virus type to be effective, ideally before the beginning of sexual activity
ObjectiveDiagnostic delay in human papillomavirus-associated oropharynx squamous cell carcinoma (HPV(+)OPSCC) is common due to nonspecific symptoms. We aim to describe the disease burden and oncolo.. Human papillomavirus type 16 (HPV16) DNA was detected in oral rinses from 54% of 124 patients with HPV-OPC at diagnosis but was persistently detected after treatment in 4% of patients with HPV-OPC. All participants with persistent oral HPV16 DNA detected after treatment experienced disease recurrence, with a median of 7.0 months between the. Objective: Human papillomavirus (HPV) assays are likely to be used with increasing frequency in clinical management of women with abnormal Papanicolaou smears and in cervical cancer screening. Our objective was to simplify the method of collection of female genital tract specimens. The utility of vaginal dry swabs for HPV diagnosis was evaluated
Molecular Diagnosis of Human Papillomavirus, Human Papillomavirus and Related Diseases - From Bench to Bedside - Research Aspects, Davy Vanden Broeck, IntechOpen, DOI: 10.5772/30165. Available from: Over 21,000 IntechOpen readers like this topic. Help us write another book on this subject and reach those readers. An abnormal Pap test is one way of making a positive HPV diagnosis in women. This page of the eMedTV archives discusses methods of diagnosing human papillomavirus (HPV). Currently, no tests are available to make a positive HPV diagnosis in men
Genital human papillomavirus (HPV) is the most common sexually transmitted infection in the United States. [1,2] An estimated 14 million persons newly infected every year, resulting in approximately $1.7 billion (estimates range from $800 million to $2.9 billion) in direct medical costs. [3 Purpose: Human papillomavirus-16 (HPV16) is the causative agent in a biologically distinct subset of oropharyngeal squamous cell carcinoma (OPSCC) with highly favorable prognosis. In clinical trials, HPV16 status is an essential inclusion or stratification parameter, highlighting the importance of accurate testing. Experimental Design: Fixed and fresh-frozen tissue from 108 OPSCC cases were. Human Papillomavirus Diagnosis The morphological alteration of cervical epithelial cells is observed through histopathological testing. Applied since the 1950s in the USA, this examination is responsible for a noticeable global reduction in cervical cancer cases
We devised a scoring system, HPV score, for histological diagnosis of human papillomavirus (HPV) infection in dysplasia of the uterine cervix. Four hundred and sixty cases of cervical dysplasia were screened for the presence of HPV infection using this system, and 116 cases (25%) were judged to be HPV infection. The results showed good correlation with those obtained using the. Papillomavirus as the cause of diseases classified elsewhere. B97.7 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2021 edition of ICD-10-CM B97.7 became effective on October 1, 2020 Approximate Synonyms. Human papilloma virus dna test positive, high risk on vaginal specimen; Human papillomavirus dna test positive, vagina; ICD-10-CM R87.811 is grouped within Diagnostic Related Group(s) (MS-DRG v 38.0):. 742 Uterine and adnexa procedures for non-malignancy with cc/mcc; 743 Uterine and adnexa procedures for non-malignancy without cc/mcc; 760 Menstrual and other female.
Approximate Synonyms. Cervical high risk human papilloma virus dna test positive; High risk human papillomavirus test positive on cervical smear; ICD-10-CM R87.810 is grouped within Diagnostic Related Group(s) (MS-DRG v 38.0):. 742 Uterine and adnexa procedures for non-malignancy with cc/mcc; 743 Uterine and adnexa procedures for non-malignancy without cc/mcc; 760 Menstrual and other female. High risk (HR) human papillomavirus (HPV), the most common sexually transmitted infection, has been identified as the major cause of cervical cancer .Scientific evidences exist which recommend HPV DNA testing in the triage of women with equivocal cytology  or in the primary cervical screening program of women aged 30 and above .The combination of cytology and HPV DNA testing. Human papillomavirus (HPV) is the most common viral infection of the reproductive tract. HPV is sexually transmitted, and most sexually active women and men will be infected at some point in their lives and some may be repeatedly infected. There are many types of HPV, and many do not cause symptoms Human papillomavirus is the most common viral infection that is transmitted through sexual activity.. Papillomaviruses are viruses that infect only humans. It is mainly a skin-borne disease. People can get an HPV infection by having vaginal, anal, or oral sex with someone infected with the virus. People with HPV may not exhibit any symptoms for years after the initial infection Failure to recognize symptoms of human papillomavirus-associated oropharyngeal squamous cell carcinoma (HPV(+)OPSCC) at presentation can delay diagnosis and treatment. This study aims to identify patient factors and provider patterns that contribute to delayed diagnosis
Human papillomavirus (HPV) infection is the most commonly diagnosed sexually transmitted disease in the United States. HPV infection has been etiologically linked with condyloma acuminatum, squamous intraepithelial lesions, and anogenital malignancy, including cervical, vaginal, vulval, penile, and anal carcinoma Differential diagnosis Molluscum contagiosum. Epidermoid cysts. Hair follicles. Sebaceous glands. Skin tags. Pearly penile papules (normal variant: 1-3 rows of smooth, discrete, non-coalescing, 1-2 mm papules appearing on the... Vulval papillomatosis (normal variant: regularly shaped,. The global Molecular Human Papillomavirus (HPV) Diagnostic Equipment market study evaluates a detailed inspection of the Molecular Human Papillomavirus (HPV) Diagnostic Equipment market, where each segment is attributed based on its Molecular Human Papillomavirus (HPV) Diagnostic Equipment market size, upcoming growth rate and key statistics Human Papillomavirus L1 Capsid Protein Detection on Cell Blocks. However, diagnosis agreement rates with tissue follow-up for CIN-1 did not increase on cell block preparations compared with LBC, because only 8 in 15 CIN-1 specimens were diagnosed as LSIL with both LBC and cell blocks. It is likely that cell block assessments for SCC and.
HPV or human papillomavirus is a group of viruses that infect human mucous membranes and skin. HPV is highly contagious. Some types of HPV are high risk, in that they are known to cause cancers of the cervix, penis, anus, vagina, vulva, and oral cavity. There are no symptoms or signs of HPV infection. Vaccines are available to prevent HPV infection BACKGROUND: Sexual behavior and oral human papillomavirus (HPV) infection are risk factors for oral squamous cell carcinoma (OSCC). The effects of OSCC diagnosis and treatment on subsequent relationship stress and sexual behavior are unknown Significant changes in sexual behavior after a diagnosis of human papillomavirus-positive and human papillomavirus-negative oral cancer. Miren Taberna MD, Department of Medical Oncology, Catalan Institute of Oncology, Bellvitge Biomedical Research Institute, L'Hospitalet de Llobregat, Barcelona, Spain The early diagnosis of a clinically inapparent, small tumor will almost certainly be highly beneficial for this patient's long-term survival. Human papillomavirus serology, as a tool to identify a population at the highest risk for development of HPV-OPC, warrants further evaluation
Human papillomavirus (HPV) produces epithelial tumors of the skin and mucous membranes. The current classification system for HPV, which is based on similarities in genomic sequences, generally correlates with the 3 clinical categories applied to HPV infection: Anogenital or mucosal (further subclassified as latent [asymptomatic], subclinica.. Human papillomavirus (HPV) is a virus that causes cervical cancer and genital warts. Over time, infection with certain types of HPV can lead to cancer of the cervix, which affects more than 10,000 American females every year. HPV can also cause cancers of the vulva and vagina in females, although these cancers are much less common than cervical.
Collect exocervical samples for the diagnosis of herpes simplex virus (HSV) and human papillomavirus (HPV), using approved collection devices and related transportation systems. Vaginal specimens Vaginal swabs can be collected with or without a speculum examination and are acceptable samples for the detection of C. trachomatis , N. gonorrhoeae. Persistent high-risk human papillomavirus (hr-HPV) infection by certain types is the main cause of cervical cancer and cervical intraepithelial neoplasia . HPV is a small (8 kb), non-enveloped, and double stranded circular DNA virus with tropism for cutaneous and mucosal epithelial cells Members of the human herpesvirus (HHV) and human papillomavirus (HPV) families cause the most common primary viral infections of the oral cavity. HPV infections have received particular attention in recent years, as high-risk strains have been linked to some cases of oral squamous cell carcinoma Comparison of Linear Array and Line Blot Assay for Detection of Human Papillomavirus and Diagnosis of Cervical Precancer and Cancer in the Atypical Squamous Cell of Undetermined Significance and Low-Grade Squamous Intraepithelial Lesion Triage Study. Research Article. 22 December 2020
INTRODUCTION. Anogenital human papillomavirus (HPV) infection is the most common sexually transmitted infection in the United States, with a prevalence of 70 million cases and an incidence of 14 million cases per year. 1-3 Fifteen high-risk (HR) HPV genotypes can lead to cancer of the cervix, anus, penis, vagina, vulva, and oropharynx. 4 Among these, the HPV-16 and HPV-18 subtypes are by far. Human Papillomavirus (HPV) infection in squamous cell carcinomas arising from the oropharynx: detection of HPV DNA and p16 immunohistochemistry as diagnostic and prognostic indicators - A pilot. KEYWORDS: cell block preparations, immunocytochemistry, liquid-based cytology, human papillomavirus L1 capsid protein, p16INK4A, Ki-67, cervical intraepithelial neoplasia. Cervical cancer is the second most frequent tumor in women worldwide, 1 and cervical intraepithelial neoplasi